A study reported in the Journal of Sexual Medicine (Vol. 10, Issue 2, 2013) sought to quantify the cost burden imposed by testosterone deficiency in men.

After examining six national databases, scientists estimated that testosterone deficiency was affecting 13.4 percent of men between the ages of 45 and 74. They also estimated that testosterone deficiency is involved in the development of approximately 1.3 million new cases of cardiovascular diseases, 1.1 million new cases of diabetes, and more than 600,000 osteoporosis-related fractures in the first year it is present.