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Home » Testosterone Shots vs Other Methods

Testosterone Cypionate Shots vs Testosterone Pellets, Creams, Gels, and Patches

At Low T Center, injection therapy is our medical team’s preferred method for replacing testosterone versus pellets, gels/creams (also referred to as topicals), or patches. Here are some of the advantages and disadvantages of each method so you can make the most informed decision when exploring TRT methods.

 

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Gels, Creams, and Patches

Topical testosterone is applied to the skin, either as a gel, cream, or patch. These options are often appealing at first because they do not involve needles.

Advantages

  • Easy to apply

  • No injections required

  • Can be done at home

Disadvantages

  • It can be messy or inconvenient for daily use

  • Testosterone may transfer through skin contact to a partner, children, or others

  • Absorption varies widely between individuals

  • Sweat, body hair, and even seasons can affect how well it works

  • Skin irritation or rashes may occur, especially with patches

  • Dosing changes are difficult to fine-tune

Because absorption is unpredictable, it can be harder for providers to keep testosterone levels steady with topicals.

Testosterone Pellets

Pellets are small cylinders of testosterone placed under the skin during a minor in-office procedure. They slowly release testosterone over time.

Advantages

  • Only requires treatment a few times per year

  • No daily routine once pellets are placed

Disadvantages

  • Requires a small surgical procedure

  • Risk of infection, irritation, or pellet rejection

  • Everyone absorbs pellets at a different rate

  • Dosage cannot be easily adjusted once pellets are inserted

  • If symptoms persist or side effects occur, changes often must wait months

Pellets may be convenient, but they offer limited flexibility if your body needs a dose change.

Testosterone Cypionate Injections

Testosterone injections deliver a measured dose directly into the body on a regular schedule, often weekly.

Advantages

  • Quick and typically well-tolerated

  • No surgical procedure required

  • Lower risk of site complications compared to pellets

  • Predictable absorption

  • Dose can be adjusted regularly based on lab results and symptoms

Disadvantages

  • Involves injections

  • Requires a consistent schedule

Because dosing can be adjusted more frequently, injections give providers greater control over treatment.

Why Injections Are Preferred at Low T Center

At Low T Center, TRT is provided using testosterone injections because they allow for:

  • Better control over testosterone levels

  • Easier dose adjustments when needed

  • More consistent monitoring over time

  • A clearer link between symptoms, labs, and treatment changes

This approach supports long-term care, not just short-term convenience.

A Quick Reminder About TRT

TRT is a medical treatment, not a one-size-fits-all solution. The right approach depends on:

  • Your symptoms

  • Your lab results

  • Your medical history

  • How your body responds over time

That is why ongoing provider oversight and regular testing are essential.

What to do next

If you are considering TRT or still deciding which option makes sense, the first step is proper testing. Low T Center offers free testosterone testing and a provider evaluation so you can get clear answers before starting treatment.

For a full explanation of eligibility, benefits, and what TRT looks like as an ongoing program, visit the main TRT page or schedule a consultation.